Scientific Research on Maca
All available third-party research on maca can be found at PubMed. A partial listing of the published research on maca is shown below:
Scientific Evidence for Effect on Sperm Count and Fertility:
- Gonzales, G. F., et al. "Effect of Black maca (Lepidium meyenii) on one spermatogenic cycle in rats." Andrologia. 2006 Oct; 38(5): 166-72.
- Bustos-Obregon, E., et al. "Lepidium meyenii (Maca) reduces spermatogenic damage induced by a single dose of malathion in mice." Asian J. Androl. 2005 Mar; 7(1): 71-6.
- Ruiz-Luna, A.C., et al. "Lepidium meyenii (Maca) increases litter size in normal adult female mice." Reprod. Biol. Endocrinol. 2005 May; 3(1): 16.
- Gonzales, C., et al. "Effect of short-term and long-term treatments with three ecotypes of Lepidium meyenii (MACA) on spermatogenesis in rats." J. Ethnopharmacol. 2006 Feb 20; 103(3): 448-54.
- Gonzales, G. F., et al. "Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m)." J. Endocrinol. 2004; 180(1): 87-95.
Scientific Evidence for Effect on Sperm Motility & Sperm Count:
- Gonzales, G. F., et al. "Lepidium meyenii (maca) improved semen parameters in adult men." Asian J. Androl. 2001; 3(4): 301–3.
- Gonzales, G. F., et al. "Effect of Lepidium meyenii (maca) roots on spermatogenesis of male rats." Asian J. Androl. 2001; 3(3): 231–33.
Scientific Evidence for Endocrine / Adrenal Actions:
- Zhang, Y., et al. "Effect of ethanol extract of Lepidium meyenii Walp. on osteoporosis in ovariectomized rat." J. Ethnopharmacol. 2006 Apr; 105(1-2): 274-9.
- Lopez-Fando, A., et al. “Lepidium peruvianum Chacon restores homeostasis impaired by restraint stress.” Phytother. Res. 2004; 18(6): 471-4.
Scientific Evidence for Anti-Depressant Actions:
- Rubio, J., et al. "Effect of three different cultivars of Lepidium meyenii (Maca) on learning and depression in ovariectomized mice." BMC Complement. Altern. Med. 2006 Jun 23; 6:23.
Scientific Evidence for Male Sexual Performance / Enhancement Actions:
- Cicero, A. F., et al. “Hexanic maca extract improves rat sexual performance more effectively than methanolic and chloroformic maca extracts.” Andrologia. 2002; 34(3): 177–79.
- Cicero, A. F., et al. “Lepidium meyenii Walp. improves sexual behaviour in male rats independently from its action on spontaneous locomotor activity.” J. Ethnopharmacol. 2001; 75(2–3): 225–29.
- Zheng, B. L., et al. “Effect of a lipidic extract from Lepidium meyenii on sexual behavior in mice and rats." Urology 2000; 55(4): 598–602.
Scientific Evidence for Hormonal Actions: (studies showing maca with a slight estrogenic action)
- Valentova, K., et al. "The in vitro biological activity of Lepidium meyenii extracts." Cell. Biol. Toxicol. 2006 Mar; 22(2): 91-9.